Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms – everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.
The biological clock regulates the expression and/or activity of enzymes and hormones involved in metabolism, and disturbance of the clock can lead to such phenomena as hormone imbalance, obesity, psychological and sleep disorders and cancer.
While light is the strongest factor affecting the circadian clock, there is a cause-and-effect relation between diet and biological clock imbalance.
In an article soon to be published by the medical industry journal Endocrinology, the researchers suggest that this high-fat diet could contribute to obesity, not only through its high caloric content, but also by disrupting the phases and daily rhythm of clock genes. They contend also that high fat-induced changes in the clock and the adiponectin signaling pathway may help explain the disruption of other clock-controlled systems associated with metabolic disorders, such as blood pressure levels and the sleep/wake cycle.
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The biological clock regulates the expression and/or activity of enzymes and hormones involved in metabolism, and disturbance of the clock can lead to such phenomena as hormone imbalance, obesity, psychological and sleep disorders and cancer.
While light is the strongest factor affecting the circadian clock, there is a cause-and-effect relation between diet and biological clock imbalance.
In an article soon to be published by the medical industry journal Endocrinology, the researchers suggest that this high-fat diet could contribute to obesity, not only through its high caloric content, but also by disrupting the phases and daily rhythm of clock genes. They contend also that high fat-induced changes in the clock and the adiponectin signaling pathway may help explain the disruption of other clock-controlled systems associated with metabolic disorders, such as blood pressure levels and the sleep/wake cycle.
EurekaAlert!
Posts, Possibly of Interest
Least Heart Failure Risk for the Lean and Active
Top 10 Tips To Stay Healthy
Top 11 Tips To A Healthy Brain
Top 10 Tips To Keep Allergies Away
Top 11 Tips To Sleep Better! - I
Top 11 Tips To Sleep Better! - II
Making the Most of Alcohol Hand Sanitizers
Top 12 Smoking Myths - I
Top 12 Smoking Myths - II
How Harmful Bacteria Can Fight off Cancer?
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