Showing posts with label Health Research. Show all posts
Showing posts with label Health Research. Show all posts

Friday, May 1, 2009

How Weight Loss Surgery Makes Life Better

Being overweight can sometimes affect our self-esteem, however, thanks to advances in medicine that today a number of weight loss techniques available, including weight loss surgery.

Since its invention, weight loss surgery or bariatric surgery has been selectively recommended to those individuals who are morbidly obese, and don't respond to conventional weight loss measures. But recent findings suggest that it may benefit moderately obese individuals as well. Let's face it, that regaining healthy weight is beneficial not only for our health, but can have a positive effect on our appearance and self-esteem too.

Speaking of health benefits, there are several reasons compelling enough, for your to consider weight loss surgery, and allow the surgeon to put you on a hospital table to trim you down.

Type 2 diabetes - Obesity is considered as the the primary risk factor for Type 2 diabetes, and so weight loss surgery can have a role to play in its reversal. But this isn't theory any more, results of a study published in the American Journal of Medicine about 82 percent patients who underwent weight loss surgery experienced diabetes reversal within a two years duration.

Fertility – Obesity can sometimes prevent women from getting pregnant. However, achieving weight loss by bariatric surgery can help improve fertility in obese women. The American Society for Reproductive Medicine suggests that weight loss can improve ovulatory functions in previously obese women.

High Blood Pressure (hypertension) – Hypertension, treated with hypertensive drugs, affects millions of Americans, according to a 2006 survey, 35.7 million visits to office-based physicians resulted in hypertension as primary diagnosis. But the good news is that that weight loss surgery can help reduce or even eliminate hypertension. The Journal of the American Medical Association (JAMA) in 2004 reported that in a study 61.7 percent patients were relieved of hypertension, while the condition of 78.5 percent improved considerably.

In addition, weight loss surgery has also been associated with easing of joint pain because it spares the joints from the stress of extra weight that overweight people carry. In general having a healthy weight can improve your health and longevity.

So while the conventional ways to lose weight may be the ideal way to deal with the problem of excess weight, weight loss surgery definitely stands by as a good alternative.

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Thursday, April 23, 2009

Can Adjustable Chairs Diminish Neck Pain?

Sitting in a chair for prolonged periods of time is a sure shot recipe for developing back and neck pain. However, if a chair such as your office chair is adjustable, then it may reduce neck and back pain that you could otherwise suffer from.

Back pain from sitting could result from several reasons. For instance, sitting in a chair or stools e.g. hospital stools, for long periods can lead to a buildup of stress on our shoulders, neck, back, arms, legs, and back muscles. In addition, most people tend to slouch while sitting, and a bad posture may make it more likely for pain to develop.

How adjustable chairs could remedy the situation.

Some time back a study published in the medical publication Spine, concluded that adjustable-height chairs that had ergonomically curved seats, had the potential to significantly reduce neck and shoulder pain in garment workplaces. (Spine, Apr 2007)

Garment workers seem to be an apt group for studying the back pain phenomenon because their work entails being seated in a position for seven to ten hours every single day. And not only do they have to work with cloth requiring fine-motor tasks while sewing, but they also have to lean forward and hold their arms and shoulders up.

Based on the results of the study the participants who were provided with an adjustable chairs had experienced a reduction in pain between 0.14 – 0.34 points on a 0-5 scale every month compared to a control group, over a four-month period.

So if adjustable chairs could work for garment workers, whose jobs are extremely physically demanding, then definitely, customizable chairs should benefit many of us who have to sit in our chairs for long hours.

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Thursday, April 16, 2009

6 Striking Health Effects of Vitamin D

According to Boston University researchers, between 30 to 50% of children and adults in the United States are at high risk for vitamin D deficiency. While this deficiency can lead to rickets in children, in adults, it is associated with cardiovascular disease, cancer, diabetes, hypertension, and immune dysfunction.

Experts believe that sensible exposure to sun, an consumption of vitamin dietary supplements may be the best way to deal with this preventable medical condition.

The following are some newly discovered benefits of vitamin D

1. Reduced risk of Fracture - A study found that oral vitamin D supplements taken at a dose of at least 400 international units daily, were linked to a decreased risk of bone fractures in older adults. (Archives of Internal Medicine, Mar 2009)

2. Protection from Diabetes - If you consume the right quantities of vitamin D, it may protect you from diabetes or even delay its onset. Further, it may reduce complications in those who've already acquired the disease. (The Diabetes Educator, 2009)

3. Prevent Heart Attacks - If you are a man and you have low levels of vitamin D in your system, then you may be at a greater risk of a heart attack or myocardial infarction, suggests a study published in the journal, Archives of Internal Medicine, June 2008 issue. Consequently, ensuring adequate amounts of the sunshine vitamin in your system via supplements may offer protection against against heart attacks.

4. Increased Girl Power! - UK researchers recently found that teenage girls with higher vitamin D levels were able to jump higher and faster than those who didn't, indicating an improved muscle performance. Boys, Watch Out! (Journal of Clinical Endocrinology and Metabolism, JCEM Feb 2009)

5. Prevent Skin Infection - A study by San Diego School of Medicine researchers found that intake of oral Vitamin D supplements helps the body produce cathelicidin - a protective chemical present in the skin. As a result, offering protection from skin infections that result from atopic dermatitis – the commonest type of eczema. (Journal of Allergy & Clinical Immunology, Oct 2008)

6. Protection from Death! - Well, vitamin D won't quite infuse immortality into you, but could make you live longer. Here's why. Following a review of several studies, French researchers concluded that the sunshine vitamin does lower your risk of death from any cause. (Archives of Internal Medicine, Sept 2007)

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Tuesday, April 14, 2009

5 Ways by which Alcohol can Abuse You

According to 2006 data, sixty one percent of American adults reported drinking alcohol during the past year. While moderate drinking is considered safe for many people, heavy drinking may be harmful to almost anyone.

Alcohol is a depressant and affects the brain much like a central nervous system drug would.

The following are some newly discovered harmful effects of alcohol

1. Cancer – Those individuals who experience facial flushing on alcohol consumption are at a greater risk of esophageal cancer. The flushing response includes nausea, facial flushing, and an increased heart rate. (PLoS Medicine, Mar 2009)

Also, alcohol consumption is the biggest risk factor for acetaldehyde-related cancer, the risk may be greater for heavy drinkers. (Addiction, Mar 2009)

Moreover, the risk of getting pancreatic cancer is upped by 22 percent by an intake of two or more alcoholic drinks per day. Advisably, men shouldn't take more than two drinks a day, while women shouldn't drink more than one. (Cancer Epidemiology, Biomarkers and Prevention, Mar 2009)

Further, a woman's chance of developing breast cancer or other cancers is increased by a margin of 13 percent, even by moderate consumption of alcoholic beverages. (Journal of the National Cancer Institute, JNCI, Mar 2009)

2. Depression - Depression is generally believed to be the cause, compelling individuals to self-medicate themselves by drinking alcohol. However, a new statistical modeling study suggests just the reverse, that in fact, excessive alcohol consumption may lead to a greater risk of depression. (Archives of General Psychiatry, Mar 2009)

Also, research shows that if you try to stop drinking, even if you're one who drinks only at moderate levels, it may lead to health problems that include depression. (Neuropsychopharmacology, Jul 2008)

3. Brain Volume – According to a new report, the more alcohol you drink lesser is your brain volume likely to be. Though, brain volume naturally decreases at a rate of 1.9 percent every decade, drinking alcohol may pronounce the effect. (Archives of Neurology, Oct 2008)

4. Pregnancy - While you're pregnant not drinking alcohol seems to be the safest option. Alcohol consumption during pregnancy has been linked to greater risks of miscarriage, stillbirth, pre-term birth, low birth-weight, etc. (The Australian and New Zealand Journal of Obstetrics and Gynaecology, Jun 2008)

5. Physical Injury – It's well-known that heavy drinking and driving don't mix, but new research shows that even with moderate consumption you could find yourself on a hospital bed. A study showed that much of alcohol linked damage is associated to moderate consumption. (A doctoral thesis, Swedish medical university Karolinska Institutet, Mar 2009).

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Thursday, April 9, 2009

Fast Ricin Detection – Is it Now Possible?

Ricin, a poison found in Castor beans is so potent that even if a small quantity, the size of a grain of salt, gets into your system can kill you. Now, if new research is to be believed, then scientists may have developed a new assay system that detects ricin fast and easy.

Perhaps the most popular incident of ricin poisoning is the 1978 assassination of the Bulgarian dissident Georgi Markov in London. He was reportedly stabbed with an umbrella that lodged a small ricin-coated pellet into his leg that later killed him. With no known antidote available, ricin today, is also feared as a potential bio-terrorism agent.

Till now, scientists had a hard time detecting the toxin. Because it involved multi-step procedures that assessed whether certain compounds were stopping ricin from working or not. But now that may not be necessary.

The New Ricin Detection Assay System

The working of the assay is simple. To check the presence of ricin in suspect samples, they need to be put into a few drops of a mixture of reagents. If the mixture emits light, then ricin is present, else it isn't. Further, the brighter the light emitted or the greater is the luminescence, higher is the concentration of the toxin within the sample. This technique has been developed by researchers at the Albert Einstein College of Medicine of Yeshiva University (AECOM).

It may appear that ricin being a poison only has nefarious applications, but no, just like nuclear energy, which can be used to generate electricity or A-bombs. Ricin too can either be used to kill humans or potentially save them. Because it has been used an cancer drug to kill and destroy cancer cells, however, this research is still in its early stages.

Nevertheless, the new ricin detection assay system should be able arm scientists with the tools that can detect ricin in a jiffy and save lives.

Wednesday, April 8, 2009

7 Foods That Affect Weight Loss

According to NIH statistics about 133.6 million or two-third of Americans were overweight or obese in 2006. Being overweight is linked to several health maladies such as heart disease, type 2 diabetes, cancers and high blood pressure to name a few.

Foods, while not the only reason contributing to excess weight gain do have a significant role to play. Other means used achieve weight change include whole food supplements, weight loss pills, physical exercise, dieting etc.

The following is a run-through of how some edibles affect weight loss or weight gain.

1. Calcium – Increasing the intake of calcium can set-off weight loss. This is the conclusion of a study that included a 15-week weight loss program, at the end of which the obese participants who consumed calcium tablets lost about 6 kg, while those who didn't lost just 1 kg. However, this worked only in people whose diets were deficient in calcium (British Journal of Nutrition, April 2009).

2. Chewing Gums – Sorbitol is the main ingredient in many sugar-free chewing gums, and it is also associated with dangerous weight loss. This was discovered after studying two patients who suffered chronic diarrhea, abdominal pain and too much weight loss, which was pinned down to eating too many chewing gums with sorbitol (British Medical Journal 'BMJ', January 2008).

But in another study, chewing gums reduced weight in a seemingly harmless way. Eating a chewing gum before an afternoon snack led to reduced food cravings via promoting fullness, and an overall reduced calorie intake, up to 25 calories. (A research presentation, 2007 Annual Scientific Meeting of The Obesity Society)

3. Grapefruit Diet – Simply supplementing your diet with grapefruit and grapefruit juice can lead to weight loss. The participants in the study who ate just half a grapefruit with a meal lost 3.6 pounds. Further, drinking grapefruit juice had a similar effect, with the participants losing 3.3 pounds ('Grapefruit Diet' study, Nutrition and Metabolic Research Center at Scripps Clinic, 2004).

4. Fructose – A reduced intake of fructose can aid weight loss. Fructose is a kind of sugar that can be quickly turned into body fat. Fruits are a good source of fructose, but so are many processed foods and the sweetener high-fructose corn syrup or HFCS, which is used in many processed foods. (Journal of Nutrition, July 2008).

5. Beverages – There's a stronger link between liquid calorie intake (e.g. beverages) and weight change than is between solid calorie intake (e.g. bread) and weight change. And that a reduction in liquid calorie intake is positively associated with weight loss (American Journal of Clinical Nutrition 'AJCN', April, 2009).

6. Dairy Products - Dairy products don't help people lose weight. This was the conclusion of evidence collected from 49 clinical trials from 1966 to 2007 that tested whether milk, and dairy products had an effect on body weight and BMI (Nutrition Reviews, May 2008).

7. Eggs - When two eggs were consumed for breakfast, as part of a reduced-calorie diet, the weight loss in overweight adults more, compared to those who ate a bagel breakfast containing an equal number of calories (International Journal of Obesity, August 2008).

Since, it's well-known that excess body weight is associated with many diseases, it appears profitable to invest time and money in weight loss, at least it's better than spending money on medical drugs used to treat excess weight related disorders.

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Herbal Supplements: 5 Promising Benefits

Results from a national survey in 2007 showed that, 17.7 percent of American adults had used "natural products" in the past 12 months. These natural or herbal supplements didn't include vitamins and minerals.

Of late there have been a slew of discussions, debates, and studies that have questioned the efficacy and safety of herbal supplements, e.g. herbal supplements viz. Echinacea, Glucosamine, Kava, etc. could lead to dangerous side effects during plastic surgery. And an NIH supported study found that the herbal supplement black cohosh used alone or with other herbal dietary supplements, wasn't effective in relieving hot flashes in postmenopausal women.

Nevertheless, the following are 5 promising health benefits of several herbal supplements.

1. Prostate Cancer Prevention - An increased consumption of dietary isoflavones is linked with reduced risk of prostate cancer. One source of the compound is Red clover (Trifolium pretense). However, there's little information about these supplements' safety. These results were reported in Cancer Prevention Research, a journal of the American Association for Cancer Research (AACR).

2. Prostate Cancer Treatment - According to a report published in the October 2005 edition of Nutrition and Cancer, Zyflamend - a unique herbal extract preparation, suppresses the growth of prostate cancer cells and causes them to self-destruct.

3. Managing Cocaine Cravings - A study presented at the American College of Neuropsychopharmacology's (ACNP) annual conference 2005, showed that the compound N-acetylcysteine (NAC) could modulate the effects of cocaine addiction. NAC is an herbal supplement known for its antioxidant properties and is sold over-the-counter.

4. Fertility Boost in women - Chasteberry was the herb that showed an improved ovulation and restoration of progesterone balance in women. These results published in the April 2004 issue of the Journal of Reproductive Medicine were an outcome of a small pilot study in by Stanford researchers. Btw, fertility is affected by a bad economy too, see: Does Bad Economy Equal Low Fertility Rate?

5. Combating Liver Cancer – The aqueous leaf extract (ALE) from the plant Acanthus ilicifolius – found across India, increased the survival of cancer ridden animals (mice) to a significant extent. Suggesting that the plant extract may be used to guard against liver cancer. The study appeared in the World Journal of Gastroenterology (volume 13, issue 48).

It's exciting to see that effective cures and treatments could very well lie outside the purview of conventional medicine. And that researches only help separate the wheat from chaff.

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Tuesday, March 31, 2009

6 Alternative Medicines For Type 2 Diabetes

With over 200 million people suffering from diabetes worldwide, and counting, it's fast becoming the #1 epidemic of modern times. A major cause of end-stage renal disease, preventable amputations and blindness, the efficacy of many alternative medicine treatments in managing diabetes has been explored.

While conventional medicine has prescriptions of endocrine disorder drugs for diabetes, alternative therapeutic approaches to its management include herbs, plant extracts and more.

The following are some naturals and alternative therapeutics that seem promising to scientists studying their effect on diabetes.

1. Fenugreek: This herb is commonly used for appetite loss, and to stimulate milk production in breastfeeding women. And a handful of studies have discovered that fenugreek may help in bringing down blood sugar levels in diabetes sufferers, that's according to the National Center for Complementary and Alternative Medicines (NCCAM).

Some time back, the Diabetes UK referred to several herbs being studied, including momordica cymbalaria, gymnema sylvestre and swertia chirayita.

2. Momordica Cymbalaria Roots: This a cucumber-like vegetable was assessed by scientists for its effect on Type 2 diabetes control and their tests on diabetic rats showed an improved glucose tolerance.

3. Gymnema Sylvestre Herb: Originating from the Indian tropical forests, this herb when tested for its effects on the body's ability to produce insulin, seemed to have a direct impact on the pancreatic insulin producing cells.

4. Swertia Chirayita Bark: Laboratory studies on the bark have found that some compounds separated from it appear to set off insulin production, in addition to enhancing its action.

5. Berberine: Chemically classified as a salt and found in the roots and barks of many plants, it has been documented in Chinese literature for having glucose lowering properties. According to Research Australia, the compound is indeed able to help lower blood sugar levels in animal models of diabetes.

6. Tai Chi Exercises:
This isn't quite a herb, nonetheless, according to the April 2008 issue of the British Journal of Sports Medicine, Tai Chi exercises can improve the management of type 2 diabetes via improving blood glucose levels.

Despite appearing promising, experts believe that a lot more research is needed to definitively establish some of these alternative medicines' degree of efficacy.

Monday, March 2, 2009

The US Biotech Industry Snapshot

The US biotechnology industry is a vibrant component of the country's economy. Since, the early 1990s the industry has registered a fast growth, with the revenues increasing from $8 billion in 1992 to $39.2 billion in 2003. Further, it is large and complex and is engaged in about 38 areas of sub‐sector elements, from plant and animal life sciences to drug discovery and information technology. The job market forecast of biological technicians, is expected to grow by 28.2 percent between 2004 and 2014.

Read More at: TheMedica

Thursday, February 26, 2009

Now Magnets May Drive Reflux Disease Away

An estimated 20 million Americans suffer from gastroesophageal reflux disease (GERD), which causes a person to experience chronic heartburn. While medical drugs helps manage the condition in the short-term, longer term relief sometimes requires surgery. But could a long term solution to the problem be hidden in modest looking magnets?

A common cause of gastroesophageal reflux disease or (GERD) is a weak or nonfunctional valve at the lower end of the esophagus (the canal that connects the mouth to the stomach), as a result the acids inside the stomach make their way into the esophagus. Since the esophagus or the food pipe isn't designed to withstand acids, the patient experiences chronic heartburn. But medics are now testing a new device which could support the function of the malfunctioning valves to treat the disease.

The New Reflux Control Device

Called the LINX Reflux Management System and introduced by Torax Medical, this device comprises a series of magnetic beads, and is meant to be placed around the bottom of the esophagus through a minimally-invasive surgical procedure, using medical instruments.

Once positioned, the magnetic attraction between the beads work in tandem with the valve and help prevent the acids to reflux, or rush up the esophagus. At the same time, the system is designed to allow food to normally pass through the esophagus to the stomach. Which is exactly what a healthy valve's function is.


According to experts, when medical therapy alone is used to treat GERD, the acids in the stomach are simply suppressed, but the underlying problem of reflux isn't cured. As a result, the most appropriate and lasting treatment for GERD would be to restore the body's own ability to avoid reflux itself.

While the new magnetic device is still being clinically tried, its real success might eventually depend on how effective it will be in comparison to other surgical procedures viz. open and Nissen fundoplications that are sometimes indicated for treating GERD.

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Friday, January 30, 2009

How Simply Writing Can Help Cancer Patients

A study published in the journal ‘The Oncologist’ in the February issue of last year supports the notion that expressive writing is effective in easing the stress of cancer. Cancers are by far one of the most dreaded medical conditions and coping with the disease can be quite stressful. Aside from the physical stress the body endures from the malady and from the various treatments viz. chemotherapy (treatment with pharma drugs), radiotherapy, etc, an individual has to cope with myriad lifestyle adjustments that induce a lot of stress.

This study indeed raises hopes that an activity as simple as expressive writing aids the individuals suffering by alleviating psychological stress arising out of the condition. Cancer is a disease that affects young and old, rich and poor and every one around the world. For example, In the year 2005 alone, the world witnessed about 7.6 million individuals becoming terminally ill with the disease. However the brighter aspect is that about 40% of all cancers are preventable and many are treatable and curable if caught early enough.

The Study

The study engaged patients in writing sessions of 20 minuets and it was found that is aided them to alter the way they thought and felt about their condition. Furthermore, this changed perception actually helped them in enhancing their quality of life.

Though, writing studies have been carried out on cancer patients before, the difference with this study was that it was conducted in a normal clinic environment as against in lab settings. Further, many writing studies involved healthy college students as subjects.

Expressive writing in the study entailed patients with leukemia and lymphoma writing about their innermost thoughts and feelings about how the disease has had and effect on them. When they were surveyed after the exercise most of them (about 50%) reported thinking and feeling differently about their condition. Further, when the exercise was repeated after three weeks an even greater number reported thinking that way (approx. 54%). On the other hand simply writing about the facts didn’t seem to have an effect on thinking patterns, the researchers found.

The following is an example of writing from the Arts and Humanities Program’s clinical weekly writing program:


The most promising finding however was that all the patient who had reported a change in their thought patterns about the disease also fared better on a quality of life measurement scale after they underwent the writing exercises.

Additionally, there were positive changes expressed in the patients’ writings as well. Many of the changes included feelings about their family, spirituality, work and the future. One patient wrote "Don't get me wrong, cancer isn't a gift, it just showed me what the gifts in my life are."

Some of the words indicative of a transformation were:

A theory explaining the finding suggests that expressing their thoughts about their chronic medical condition causes psychological as well as physiological changes to occur. However, researchers also believe that that there's a whole array of reasons why expressive writing benefits.

Benefits go beyond cancer

The benefits of expressive writing are not confined to cancer patients only. Several other researches on the topic have revealed that it helps in numerous medical conditions such as asthma, arthritis and pelvic pain. Other studies indicate the benefits to be an improved immune system, pain relief - what a way to relieve pain without a pain relief drug.

While writing research isn’t new and it has been conducted for the past 20 years or so, it’s now time to bring the benefits out to the patients. Not only has writing been found to be effective, it’s perhaps the most cost-effective means of coping.

Another question that arises is, whether the benefits of writing are confined only to those suffering from chronic and challenging medical conditions? Given the evidence of research carried out, it appears that simply writing about intensely positive experiences helps too. A study published by the Department of Psychological Sciences, University of Missouri found that writing about IPEs or intensely positive experiences was associated with enhanced positive mood, and it was also linked to fewer health center visits for illness. Health benefits of writing have also been echoed by in the Journal of Clinical Psychology, by University of Texas researchers James Pennebaker, and Janet Seagal.

In order to reap the benefits of writing you don’t have to wait, you can begin writing right away. You might begin with short sessions of 15 – 20 minuets and increasing the time you spend writing, as you become comfortable with the activity. If you’re attempting to journal for the first time you could have some doubts in your mind but all you have to do is to express yourself and leave aside any fears and inhibitions. With a little practice, fluidity would come to your writing by itself. The only instruments you need for it are a pen and a journal or you might even choose to blog your way to expressing yourself.

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Study: Stem Cell Transplant Reverses Multiple Sclerosis

Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems.

"This is the first time we have turned the tide on this disease," said principal investigator Richard Burt, M.D. chief of immunotherapy for autoimmune diseases at the Feinberg School. The clinical trial was performed at Northwestern Memorial Hospital where Burt holds the same title.

The patients in the small phase I/II trial continued to improve for up to 24 months after the transplantation procedure and then stabilized. They experienced improvements in areas in which they had been affected by multiple sclerosis including walking, ataxia, limb strength, vision and incontinence. The study will be published online January 30 and in the March issue of The Lancet Neurology.

"We focus on destroying only the immune component of the bone marrow and then regenerate the immune component, which makes the procedure much safer and less toxic than traditional chemotherapy with cancer drugs," Burt said. After the transplantation, the patient's new lymphocytes or immune cells are self-tolerant and do not attack the immune system.

"In MS the immune system is attacking your brain," Burt said. "After the procedure, it doesn't do that anymore."

In previous studies, Burt had transplanted immune stem cells into late-stage MS patients. "It didn't help in the late stages, but when we treat them in the early stage, they get better and continue to get better," he said.

Source: EurekAlert!

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Thursday, January 29, 2009

Are Best Hospital Lists Worth their Salt?

Recently, a study found that the top-rated U.S. hospitals had a 27 percent lower death rate than other hospitals. So are the best ranked hospitals within the healthcare market really the best places for patients to seek treatment from.a king's crown

They probably are to quite an extent and the ratings more credible if it's also known that the health care ratings organization is an independent one, such as is the case with HealthGrades.

So many top-rank lists

But consulting a single organization's ranking lists might not serve to be the final answer in your search for the best place to get medical care from. Perhaps, including the results of other agencies such as the Leapfrog Group, which surveys over 1,300 hospitals nationally, or The Joint Commission, which tracks different kinds of medical care rendered, or even the U.S. News' analysis of more than 5,453 medical centers to produce an Honor Roll based on 16 specialty rankings may also come in handy.

However, referring to several such reports, might at times, turn out to be confusing, because they might not appear to agree on who the best hospitals after all are. And some of the very best on one list simply might not figure on another. For instance, if one study analyzes just high volume and low risk procedures, while the other takes account of difficult and highly specialized treatments, the results would naturally be quite different. Or if one just assessed the hospitals' equipment & supplies, the outcomes would be radically different.

Cheeky Critics

Also, despite these lists being reliable in assessing the factors they rate the health care facilities on, are not without critics. The much debated Federal nursing home rating system is a glaring example, as some think that the assessment doesn't consider a broader view of all that takes place inside nursing homes. Nevertheless, it does consider something, which is better than nothing.

It seems in the end that many of these lists do provide reliable assessments, but search for a perfect hospital should always take into account the patient and her family's needs and limitation. As a result the top rank lists would be truly meaningful when they are used while considering the proximity, the abnormal medical condition, the medical procedure advised, affordability, and a host of such factors for which the patient and her family are perhaps the best judges.

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Tuesday, January 27, 2009

How to choose the right gloves for cleanroom gloveboxes?

Glove box gloves come in a wide variety incorporating different materials and designs. The importance of using the right kind of gloves can't be ignored because it can have negative repercussions on operational effectiveness, safety, cost and dexterity for the cleanroom staff as well as the object handled. Consequently, a forethought before the final purchase decision based on some information about the types of options available and other considerations, will help you make the right purchase.

Read More at: Themedica

Thursday, January 15, 2009

Atypical Antipsychotic Drugs Increase Risk Of Sudden Cardiac Death In Adults

Patients ages 30 to 74 who took atypical antipsychotic pharmaceutical drugs such as risperidone (sold as Risperdal), quetiapine (Seroquel), olanzapine (Zyprexa) and clozapine (Clozaril) had a significantly higher risk of sudden death from cardiac arrhythmias and other cardiac causes than patients who did not take these medications, according to a new study funded by HHS' Agency for Healthcare Research and Quality. The risk of death increased with higher doses of the drugs taken.

The study, titled "Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death," is published in the January 15 issue of the New England Journal of Medicine.

Atypical antipsychotics are commonly used to treat schizophrenia and bipolar disorders. They are also prescribed "off label" for symptoms such as agitation, anxiety, psychotic episodes and obsessive behaviors. Atypical antipsychotics are less likely to cause tremors and other serious movement disorders that affect users of typical antipsychotics.

"This study provides critical information about the safety of atypical antipsychotics that can be used to make important treatment decisions for patients," said AHRQ Director Carolyn M. Clancy, M.D. "These findings will help clinicians and patients weigh the risks versus the benefits of these drugs before prescribing them for treatment of depression or other off label uses for other conditions."

Lead researcher Wayne A. Ray, Ph.D., and his colleagues at AHRQ's Center for Education and Research on Therapeutics at Vanderbilt University in Nashville found that current users of atypical antipsychotic drugs had a rate of sudden cardiac death twice that of people who didn't use the drugs and similar to the death rate for patients taking typical antipsychotics, including haloperidol (Haldol) and thioridazine (Mellaril).

Researchers reviewed medical records from the Tennessee Medicaid program and identified data on patients prescribed atypical antipsychotics, including the number of prescriptions they received, the dose and the number of days supplied. Researchers conclude that atypical antipsychotics are not a safer alternative to typical antipsychotics in preventing death from sudden cardiac causes.

The CERTs program, established in 1999, is a research program administered by AHRQ in consultation with the U.S. Food and Drug Administration. The overarching goal is to serve as a trusted national resource for people seeking to improve health through the best use of medical therapies. The CERTs program includes partnerships of public and private organizations, a national steering committee involving multiple sectors and the CERTs investigators, a coordinating center and 14 research centers.

Source: AHRQ

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Wednesday, January 14, 2009

Pee on Paper to Treat TB – Here's How?

Effective treatment of tuberculosis entails adhering to lengthy TB pharma drugs regimen. To ensure that people follow through the duration of treatment scientists have found a clever way in which simply peeing on paper can lead you to comply with treatment.

Tuberculosis or TB is an airborne infectious disease that's curable. However it requires strict compliance with TB drugs for months. And many people, especially in poor countries drop out in the middle because the drugs can trigger nausea and other side effects. This in turn is leads to a relapse with drug resistant strains of bacteria, making treatment difficult. The consequences are evident from TB statistics. According to the WHO, TB afflicts millions worldwide – of the 9.2 million cases newly diagnosed in 2006, 1.7 million people succumbed to the disease.

The Pee based approach to TB treatment

Staff from the Innovations in International Health (IIH) project at MIT, recently devised a program which uses paper-based diagnostics called “XoutTB” with text-messaging technology and service to improve tuberculosis (TB) treatment compliance in poor countries.

At the heart of the program lies a rewards schedule, whereby patients complying with to the TB drug regimens consistently for 30 days are rewarded with cell-phone minutes, encouraging them further.

To track compliance, the participants are required to pee on a paper-based diagnostic equipment, which is dispensed once each day. The device is able to detect the metabolites of the TB drug in urine – accurately assessing whether the drugs were consumed or not. Also the reaction between the drug molecules in urine and the chemicals embedded in the paper devices uncover a code that the participants need to text-message to a central database. A consistent record of compliance for 30 days is rewarded with free minuets.

It's simple and hopefully will turn out to be quite effective, as the trials are still on. While the real work is still accomplished by the good old TB drugs, the pee based diagnostics are central to making that happen. Now, that's what I'd call real waste management!

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Tuesday, January 13, 2009

Vicks VapoRub Misuse May Harm Toddlers

Vicks® VapoRub®, the popular salve used to relieve symptoms of cough and congestion, may be harmful for infants and toddlers. New research appearing in the January issue of CHEST, the peer-reviewed medical industry journal of the American College of Chest Physicians (ACCP), shows that Vicks® VapoRub® (VVR) may stimulate mucus production and airway inflammation, which can have severe effects on breathing in an infant or toddler. Research findings are consistent with current VVR labeling which indicates the product should not be used on children under 2 years of age.

VVR is not indicated for patients under age 2. However, Dr. Rubin realizes that some parents are still choosing to use VVR to relieve their sick young child's symptoms, usually rubbing the salve on the feet or chest.

"I recommend never putting Vicks in, or under, the nose of anybody—adult or child. I also would follow the directions and never use it at all in children under age 2," said Dr. Rubin.

Dr. Rubin also feels that although the study only tested Vick's VapoRub, similar products, including generic brands, could cause the same adverse reaction in infants and toddlers.

"The best treatments for congestion are a bit of saline (salt water) and gentle rubber bulb suction, warm drinks or chicken soup, and, often, just letting the passage of time heal the child." Dr. Rubin also notes that if a child is struggling to breathe, it is a medical emergency and would require the child to be seen by a doctor as quickly as possible.

"Parents should consult with a physician before administering any over-the-counter medicine to infants and young children," said James A. L. Mathers, Jr., MD, FCCP, President of the American College of Chest Physicians. "Furthermore, the American College of Chest Physicians and several other health-care organizations have concluded that over-the-counter cough and cold medicines can be harmful for infants and young children and are, therefore, not recommended."

Source: EurekAlert!

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Friday, January 9, 2009

California's Autism Cases Rising!

A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.

Published in the January 2009 issue of the journal Epidemiology, results from the study also suggest that research should shift from genetics to the host of chemicals and infectious microbes in the environment that are likely at the root of changes in the neurodevelopment of California's children.

"It's time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California," said UC Davis M.I.N.D. Institute researcher Irva Hertz-Picciotto, a professor of environmental and occupational health and epidemiology and an internationally respected autism researcher.

Hertz-Picciotto said that many researchers, state officials and advocacy organizations from the medical industry have viewed the rise in autism's incidence in California with skepticism.

The incidence of autism by age six in California has increased from fewer than nine in 10,000 for children born in 1990 to more than 44 in 10,000 for children born in 2000. Some have argued that this change could have been due to migration into California of families with autistic children, inclusion of children with milder forms of autism in the counting and earlier ages of diagnosis as consequences of improved surveillance or greater awareness.

Hertz-Picciotto said that the study is a clarion call to researchers and policy makers who have focused attention and money on understanding the genetic components of autism. She said that the rise in cases of autism in California cannot be attributed to the state's increasingly diverse population because the disorder affects ethnic groups at fairly similar rates.

"We're looking at the possible effects of metals, pesticides and infectious agents on neurodevelopment," Hertz-Picciotto said. "If we're going to stop the rise in autism in California, we need to keep these studies going and expand them to the extent possible."

UC Davis Health System News

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Monday, December 29, 2008

Caution: High-Fat Diet Can Disrupt Your Biological Clock!

Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms – everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.

The biological clock regulates the expression and/or activity of enzymes and hormones involved in metabolism, and disturbance of the clock can lead to such phenomena as hormone imbalance, obesity, psychological and sleep disorders and cancer.

While light is the strongest factor affecting the circadian clock, there is a cause-and-effect relation between diet and biological clock imbalance.

In an article soon to be published by the medical industry journal Endocrinology, the researchers suggest that this high-fat diet could contribute to obesity, not only through its high caloric content, but also by disrupting the phases and daily rhythm of clock genes. They contend also that high fat-induced changes in the clock and the adiponectin signaling pathway may help explain the disruption of other clock-controlled systems associated with metabolic disorders, such as blood pressure levels and the sleep/wake cycle.

EurekaAlert!

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Is Greater use of Imaging Technology Justified?

During the past several years, the availability of computed tomography (CT) and magnetic resonance imaging (MRI) scanning has grown rapidly. An estimated number of CT diagnostic equipment units grew more than 50 percent between 1995 and 2004, while the estimated number of MRI units more than doubled. Apparently, the use of imaging technologies has associated costs and benefits, the question is whether the benefits are more than costs or not? An insightful study conducted by Stanford University researchers recently published brought the issue into the limelight.

Read More at: Themedica